Lupus
Immune Complexes
& the ANA Test
un
seel
.com · nuclear antigen · autoantibody · complement · nephritis
ANA titer
—
C3 / C4
normal
stage
tolerant
state
—
Nuclear antigen (dsDNA · histone · Sm)
Anti-nuclear autoantibody / immune complex
Complement (C3 / C4) & interferon-alpha
Glomerulus · ANA readout · therapy
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.com · Systemic Lupus Erythematosus: Immune Complexes and the ANA Test